Some people take melatonin by mouth to adjust the body's internal clock. It is used for jet lag, for adjusting sleep-wake cycles in people whose daily work schedule changes (shift-work disorder), and for helping blind people establish a day and night cycle.
Melatonin is also taken by mouth for the inability to fall asleep (insomnia); delayed sleep phase syndrome (DSPS); rapid eye movement sleep behavior disorder (RBD); insomnia associated with attention deficit-hyperactivity disorder (ADHD); insomnia associated with traumatic brain injury (TBI); and sleep problems in children with developmental disorders including autism, cerebral palsy, and intellectual disabilities. It is also taken by mouth as a sleep aid after discontinuing the use of benzodiazepine drugs and to reduce the side effects of stopping smoking.
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Melatonin's main job in the body is to regulate night and day cycles or sleep-wake cycles. Darkness causes the body to produce more melatonin, which signals the body to prepare for sleep. Light decreases melatonin production and signals the body to prepare for being awake. Some people who have trouble sleeping have low levels of melatonin. It is thought that adding melatonin from supplements might help them sleep.